The biggest cause of depression is change. So change can be a very bad thing for those that don't like change.
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Or we can look at the lighter side of the end of the world as it relates to different groups and individuals.
Christians and kids, since it ends on Dec 26, there is one last Christmas
Republicans. If Obama is re-elected, he will never serve a second term
Democrats. If Palin wins, she will never take office.
Israelis. They can hold out that long without giving up settlements in the Golan Heights.
Bernie Madoff won't have to serve his entire term (well the part on Earth)
The Iraq and Afghanistan wars will finally end.
The recession will come to an early end (not sure that is really good).
DTV will be replaced with GTV (well if God has TV?)
All the space junk won't matter any more.
Many divorces will be final.
It will end illegal immigration
No one will be around to pay off the deficit.
Iran will have no one to use their bomb on.
and
Doomsayers will have their wish, finally.