Lost 2 functions on a remote - DirecTV

The down option is not working on both the volume and channel controls.
Batteries are good. Tried to resync by holding the mute and enter buttons as suggested but it never went to "applying ir/rf set up". Should I reset receiver which is next option listed?

This question, "Lost 2 functions on a remote," is about DirecTV channels, programming, equipment, and sports.